Author

M. Spanou

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. B. Benowitz· 1 shared A. Konopacka· 1 shared A. Saudemont· 1 shared C. M. Deane· 1 shared C. Martinez-Fleites· 1 shared G. P. Heger· 1 shared H. An· 1 shared L. Gordon· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. B. Benowitz

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1 paper

Recent·Most cited

Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells

P. J. Brennan, R. E. Saunders, M. Spanou, M. Serafini, L. Sun, G. P. Heger, A. Konopacka, R. D. Beveridge, L. Gordon, S. B. Bunally, A. Saudemont, A. B. Benowitz, C. Martinez-Fleites, M. A. Queisser, H. An, , S. J. Conway

The paper designs a selective protein degradation system using bumped IMiD analogs and zinc-finger degrons to target specific proteins without affecting endogenous substrates.

bioRxiv · Mar 15, 2024Biochemistry