Human brain changes after first psilocybin use
Timothy Lyons, M. Spriggs, Leevi Kerkelä, Fernando E. Rosas, Leor Roseman, Pedro A. M. Mediano, Christopher Timmermann, Lena Oestreich, Broc A. Pagni, Richard J. Zeifman, Adam Hampshire, William R. Trender, Hannah M. Douglass, Manesh Girn, Kate Godfrey, , Robin Lester Carhart-Harris
This study investigates brain changes after a single high-dose psilocybin administration, finding anatomical and functional alterations linked to improved well-being and cognitive flexibility.
Nature Communications · May 5, 2026Peer-reviewedNeuroscience