Author

C. Lewis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cancer Biology· 1 Cell Biology· 1 Ecology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

B. Lawrence· 2 shared H. Levis· 2 shared R. D. Bowles· 2 shared A. Aleotti· 1 shared A. B. Rohrlach· 1 shared A. Ballesteros-Tato· 1 shared A. Ediriweera· 1 shared A. F. Rosenberg· 1 shared

Activity by Year

2020-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersBioengineering

B. Lawrence

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

ZNF865 Regulates Senescence and Cell Cycle for Applications to Cell Engineering and Gene Therapy

H. Levis, C. Lewis, E. Stockham, J. D. Weston, A. Lawal, B. Lawrence, S. E. Gullbrand, R. D. Bowles

This study identifies ZNF865 as a regulator of senescence and cell cycle, demonstrating its potential for cell engineering and gene therapy applications.

bioRxiv · Oct 25, 2023Bioengineering

Exploring archaeogenetic studies of dental calculus to shed light on past human migrations in Oceania

I. M. Velsko, Z. Fagernas, M. Tromp, S. Bedford, H. Buckley, G. Clark, J. Dudgeon, J. L. Flexner, A. Leal-Tamarii, C. Lewis, M.-S. Lisa, K. Nagele, A. Ozga, A. B. Rohrlach, C. Posth, , C. Warinner

This study analyzes dental calculus metagenomes from 103 ancient Pacific individuals to explore their potential in understanding past human migrations.

bioRxiv · Oct 18, 2023 · PreprintMicrobiology

Therapeutic TNF-alpha Delivery After CRISPR Receptor Modulation in the Intervertebral Disc

J. D. Stover, M. A. R. Trone, J. Weston, C. Lewis, H. Levis, M. Philippi, M. Zeidan, B. Lawrence, R. D. Bowles

This study uses CRISPR to modulate TNFR1 in rats, reducing disc degeneration and showing that TNF-alpha injection becomes therapeutic after receptor modulation.

bioRxiv · May 31, 2023Bioengineering

The origin, evolution and molecular diversity of the chemokine system

A. Aleotti, M. Goulty, C. Lewis, F. Giorgini, R. Feuda

This study investigates the origin and evolution of the chemokine system, revealing independent evolution of chemokine-like functions and vertebrate-specific receptor origins.

bioRxiv · May 17, 2023Evolutionary Biology

Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease

Z. Wang, S. Zhu, Y. Jia, Y. Wang, N. Kubota, N. Fujiwara, R. Gordillo, C. Lewis, M. Zhu, T. Sharma, L. Li, Q. Zeng, Y.-H. Lin, M.-H. Hsieh, P. Gopal, , H. Zhu

The paper identifies adaptive pathways in metabolic liver disease by selecting somatically mutated clones in mice and humans, finding mutations that ameliorate lipotoxicity and promote clonal expansion.

bioRxiv · Mar 20, 2023Cell Biology

IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

H. Bachus, E. McLaughlin, C. Lewis, A. M. Papillion, E. N. Benveniste, D. D. Hill, A. F. Rosenberg, A. Ballesteros-Tato, B. Leon

This study shows IL-6 prevents Th2 cell polarization by suppressing IL-2 signaling through SOCS3, reducing allergic inflammation and IgE response.

bioRxiv · Dec 5, 2022Immunology

Prediction of Electric Fields Induced by Transcranial Magnetic Stimulation in the Brain using a Deep Encoder-Decoder Convolutional Neural Network

M. Tashli, M. S. Alam, J. Gong, C. Lewis, C. L. Peterson, H. Eldardiry, J. Atulasimha, R. L. Hadimani

This paper develops a deep convolutional neural network to predict induced electric fields from TMS in real-time using MRI data, achieving high accuracy with peak signal-to-noise ratios of 32.83dB and 28.01dB.

bioRxiv · Oct 27, 2022 · PreprintBioengineering

Pleiotrophin drives a pro-metastatic immune niche within the breast tumor microenvironment

D. Ganguly, M. O. Schmidt, M. Coleman, T.-V. Ngo, N. Sorrelle, A. T. Dominguez, J. Toombs, C. Lewis, Y. Fang, F. V. Mora, D. Gallego-Ortega, A. Wellstein, R. A. Brekken

This study identifies pleiotrophin as a driver of a pro-metastatic immune niche in breast cancer, showing its role in immune suppression and metastasis, and highlights its potential as a therapeutic target.

bioRxiv · May 2, 2022Cancer Biology

Effects of face masks on acoustic analysis and speech perception: Implications for peri-pandemic protocols

M. Magee, C. Lewis, G. Noffs, H. Reece, J. C. S. Chan, C. J. Zaga, C. Paynter, O. Birchall, S. Rojas Azocar, A. Ediriweera, M. W. Caverle, B. G. Schultz, A. P. Vogel

This study examines how different face masks affect speech acoustics and intelligibility, finding changes in frequency distribution and spectral features but no impact on word or sentence intelligibility.

The Journal of the Acoustical Society of America · Dec 1, 2020Peer-reviewedBioengineering

Rapid Population Decline of the Pillar Coral Dendrogyra cylindrus Along the Florida Reef Tract

K. L. Neely, C. Lewis

The paper tracks the population decline of pillar coral Dendrogyra cylindrus on the Florida Reef Tract, finding reproductive extinction and functional extinction due to stressors like coral bleaching and stony coral tissue loss disease.

bioRxiv · May 9, 2020Ecology