3D culture of pancreatic cancer cells in vitro recapitulates an aberrant mitochondrial oxidative phosphorylation genotype observed in vivo
J. M. Treherne, K. Kus, M. P. Krzykawski, D. L. Earnshaw, R. Krzykawska, B. Biesaga, M. Statkiewicz, K. Unrug-Bielawska, Z. Sandowska-Markiewicz, M. Mikula, J. A. Alfaro
This study shows that 3D cultures of pancreatic cancer cells better replicate the mitochondrial oxidative phosphorylation genotype seen in vivo compared to 2D cultures.
bioRxiv · Mar 8, 2024 · PreprintCancer Biology