Tales of 1,008 Small Molecules: Phenomic Profiling through Live-cell Imaging in a Panel of Reporter Cell Lines
M. J. Cox, S. Jaensch, J. Van de Waeter, L. Cougnaud, D. Seynaeve, S. Benalla, S. J. Koo, I. Van Den Wyngaert, J.-M. Neefs, D. Malkov, M. Bittremieux, M. Steemans, P. J. Peeters, J. K. Wegner, H. Ceulemans, , H. W. H. Göhlmann
The paper uses live-cell imaging of reporter cell lines to profile 1,008 compounds, identifying their mechanisms of action with high accuracy.
bioRxiv · Mar 13, 2020Pharmacology & Toxicology