Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo
J. Singh, H. Elhabashy, P. Muthukottiappan, M. Stepath, M. Eisenacher, O. Kohlbacher, V. Gieselmann, D. Winter
The paper uses cross-linking mass spectrometry to identify protein structures and cargo associated with lysosomes and early endosomes, revealing tetrameric PPT1 and flotillin complexes.
bioRxiv · Jan 12, 2022 · PreprintBiochemistry