Defining levels of dengue virus serotype-specific neutralizing antibodies induced by a live attenuated tetravalent dengue vaccine (TAK-003)
L. White, E. Young, M. Stoops, S. Henein, R. S. Baric, A. De Silva
This study characterizes the serotype-specific neutralizing antibody responses induced by the tetravalent dengue vaccine TAK-003 in humans and non-human primates, finding that DENV2 is immunodominant while DENV1, 3, and 4 responses are lower and cross-reactive.
bioRxiv · Sep 23, 2020Immunology