Embracing enzyme promiscuity with activity-based compressed biosensing
B. A. Holt, H. S. Lim, M. Su, M. Tuttle, H. Liakakos, P. Qiu, G. A. Kwong
This paper introduces SLICE, a method to select promiscuous protease substrates for compressed sensing, enabling accurate classification of complex protease mixtures with fewer substrates.
bioRxiv · Jan 4, 2022Bioengineering