Author

M. Uni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Kentsis· 2 shared S. Cheng· 2 shared S. Takao· 2 shared A. Slavit· 1 shared C. Chen· 1 shared C. R. Vakoc· 1 shared F. C. Brown· 1 shared G. Minuesa· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

A. Kentsis

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2 papers

Recent·Most cited

Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance

S. Takao, V. Morell, M. Uni, A. Slavit, S. Rha, S. Cheng, L. K. Schmalbrock, F. C. Brown, S. B.- Calabuig, R. Koche, L. Velten, A. Kentsis

This study identifies a quiescent label-retaining cell population in human AML that drives disease and therapy resistance through epigenetic mechanisms.

bioRxiv · Sep 22, 2022Cancer Biology

Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia

S. Takao, L. Forbes, M. Uni, S. Cheng, J. M. B. Pineda, Y. Tarumoto, P. Cifani, G. Minuesa, C. Chen, M. G. Kharas, R. K. Bradley, C. R. Vakoc, R. P. Koche, A. Kentsis

This study identifies aberrant MYB complex assembly as a driver of oncogenic gene expression in AML and shows that targeting this complex can induce differentiation and apoptosis.

bioRxiv · May 5, 2020Cancer Biology