Interplay between Desmoglein2 and hypoxia controls metastasis in breast cancer
P.-H. Chang, M.-C. Chen, Y.-P. Tsai, G. Y. T. Tan, P.-H. Hsu, Y.-M. Jeng, Y.-F. Tsai, M.-H. Yang, W. W. Hwang-Verslues
This study identifies DSG2 as a key factor in breast cancer metastasis, showing that hypoxia dynamically regulates DSG2 to control tumor cell dissemination and colonization.
bioRxiv · Nov 9, 2020Cancer Biology