Author

Mackenzie Heck

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander L. RakhmilevichiD· 3 shared Alina A. HamptoniD· 3 shared Amy K. ErbeiD· 3 shared Arika S. FeilsiD· 3 shared Jen ZaborekiD· 3 shared Mildred A. R. Felder· 3 shared Noah W. TsarovskyiD· 3 shared Belinda B. WenkeiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Alexander L. RakhmilevichORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bispecific GD2xB7-H3 Antibody Improves Tumor Targeting and Reduces Toxicity while Maintaining Efficacy for Neuroblastoma

Amy K. Erbe, Arika S. Feils, Sabrina Reinthaler, Alina A. Hampton, Zachary T. Rosenkrans, Yadira Medina-Guevara, Mildred A. R. Felder, Jessica M. Wiwczar, Daniel Gerhardt, Mark R. Bercher, Belinda B. Wenke, Callie Haertle, Mackenzie Heck, Kaia Heimstreet, Elizabeth Frankel, , PaulM. Sondel

This paper describes a bispecific antibody that targets GD2 and B7-H3 to improve tumor targeting and reduce toxicity in neuroblastoma treatment.

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

Immune-mediated Engagement of T Regulatory Cells with Tumor Cells Results in Trogocytosis and Tumor Cell Killing.

Amy K. Erbe, Arika S. Feils, Anqi Gao, Sabrina N. VandenHeuvel, Simon Boyenga, Alina A. Hampton, Mackenzie Heck, Jen Zaborek, Daniel Spiegelman, Noah W. Tsarovsky, Anna Hoefges, Alexander A. Pieper, Peter M. Carlson, Mildred A. R. Felder, Ravi B. Patel, , Paul M. Sondel

The paper shows CD4 T regulatory cells can kill tumor cells through trogocytosis after immunocytokine treatment in a melanoma model.

bioRxiv · Dec 23, 2025 · PreprintCancer Biology

Bispecific GD2 x B7-H3 Antibody Improves Tumor Targeting and Reduces Toxicity while Maintaining Efficacy for Neuroblastoma

Amy K. Erbe, Arika S. Feils, Alina A. Hampton, Zachary T. Rosenkrans, Mildred A. R. Felder, Jessica M. Wiwczar, Daniel J. Gerhardt, Mark R. Bercher, Belinda B. Wenke, Callie Haertle, Mackenzie Heck, Sabrina N. VandenHeuvel, Lizzie Frankel, Megan Nielsen, Dan Spiegelman, , Paul M. Sondel

bioRxiv · May 23, 2024 · PreprintCancer Biology