Author
Mai Saeki
Institute for Quantitative Biosciences, The University of Tokyo
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2023-2026 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author links6 papers
Recent·Most cited
Sex-biased transcriptome in embryonic mouse cortices under Pax6 haploinsufficiency highlights Pbdc1 as a candidate regulator
Shyu Manabe, Shohei Ochi, Takako Kikkawa, Sharmin Naher, Mai Saeki, Kohdai Yamada, Hidetaka Kosako, Yusuke Kishi, Tatsuya Sawasaki, Noriko Osumi
The paper identifies sex-biased transcriptome changes in Pax6 haploinsufficient mouse cortices and highlights Pbdc1 as a candidate regulator of sex-dependent corticogenesis.
bioRxiv · Oct 19, 2025 · PreprintDevelopmental Biology
Age-associated transcriptomic and epigenetic alterations in mouse hippocampus
Merve Bilgic, Rinka Obata, Vlada‐Iuliana Panfil, Ziying Zhu, Mai Saeki, Yukiko Gotoh, Yusuke Kishi
This study identifies age-related transcriptomic and epigenetic changes in mouse hippocampus, highlighting cell-type-specific alterations in chromatin accessibility and gene regulation.
Aging Cell · Sep 28, 2025Peer-reviewedNeuroscience
In vivo transition in chromatin accessibility during differentiation of deep-layer excitatory neurons in the neocortex
Seishin Sakai, Yurie Maeda, Mai Saeki, Daijiro Konno, Keita Kawaji, Fumio Matsuzaki, Yutaka Suzuki, Yukiko Gotoh, Yusuke Kishi
The paper tracks chromatin accessibility changes in mouse embryonic deep-layer excitatory neurons during differentiation using RNA-seq and DNase-seq.
Development · Jun 12, 2025Peer-reviewedDevelopmental Biology
Neuronal migration induces DNA damage in developing brain
Zhejing Zhang, Andrés Canela, Peilin Zou, Takahiro Furuta, Noriko Takeda, Takumi Kawaue, Naotaka Nakazawa, Mai Saeki, Maki Utsunomiya, Junko Kurisu, Fumiyoshi Ishidate, Hiroyuki Sasanuma, Yusuke Kishi, Mineko Kengaku
The paper shows neuronal migration in developing brains causes DNA damage through mechanostress, which is repaired normally but can lead to disease if unresolved.
bioRxiv · Jun 10, 2025 · PreprintCell Biology
Propagation of neuronal micronuclei regulates microglial states
Sarasa Yano, Natsu Asami, Yusuke Kishi, Hikari Kubotani, Yuki Hattori, Ayako Kitazawa, Kanehiro Hayashi, Ken‐ichiro Kubo, Mai Saeki, Chihiro Maeda, Kaito Akiyama, Tomomi Okajima, Ban Sato, Yukiko Gotoh, Kazunori Nakajima, , Fuminori Tsuruta
This study shows neuronal micronuclei influence microglial states by altering their morphology and transcriptome during postnatal development.
bioRxiv · Jul 31, 2023 · PreprintNeuroscience