Manami Morimoto

Environment-specific mechanosensing preserves a common bleb-based migratory program across diverse embryonic environments

The paper shows chick primordial germ cells use a common bleb-based migratory program across different embryonic environments, with distinct molecular mechanisms in each context.

Bleb-based extravasation: conserved morphodynamics, divergent calcium control

The paper shows that all extravasating cells form Ca²⁺-dependent membrane blebs, but the source of Ca²⁺ varies by lineage, highlighting distinct regulatory mechanisms.

The yolk sac vasculature in early avian embryo provides a novel model for the analysis of cancer extravasation

The paper uses the yolk sac vasculature of early avian embryos to study cancer cell extravasation, showing distinct morphologies and dynamics through fluorescent labeling.

The SOCE system is critical for membrane bleb formation to drive avian primordial germ cell migration

The paper shows that SOCE-mediated Ca2+ elevation drives membrane bleb formation in avian PGCs, essential for in vivo migration.