Author

Manish Rai

Institute of Genomics and Integrative Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:metagenomics· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akanksha SharmaiD· 2 shared Devi Prasanna Dash· 2 shared Kausik ChakrabortyiD· 2 shared Zainab Zaidi· 2 shared Abhishek Bhatt· 1 shared Aksheev BhambriiD· 1 shared Ankit VermaiD· 1 shared Bastian FrommiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersEvolutionary Biology

Akanksha SharmaORCID

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3 papers

Recent·Most cited

Laboratory adaptive evolution of thermotolerance is linked to the evolution of a robust proteostasis in S. cerevisiae

Devi Prasanna Dash, Zainab Zaidi, Akanksha Sharma, Dhwani Dholakia, Manish Rai, Debasish Dash, Kausik Chakraborty

This study shows that adaptive evolution in yeast increases ERAD capacity to improve thermotolerance by enhancing proteostasis under thermal stress.

bioRxiv · Jan 31, 2025 · PreprintEvolutionary Biology

Fitness defects due to cytosolic protein misfolding in S. cerevisiae can be alleviated by decreasing mitochondrial protein import capacity

Zainab Zaidi, Devi Prasanna Dash, Akanksha Sharma, Soumen Kundu, Sarika Bhatt, Shikha Rao, Kedar Padia, Manish Rai, Kausik Chakraborty

The paper identifies that reducing mitochondrial protein import capacity alleviates cytosolic protein misfolding fitness defects in yeast by enhancing proteostasis.

bioRxiv · Aug 26, 2024 · PreprintMolecular Biology

Insights into regeneration from the genome, transcriptome and metagenome analysis of Eisenia fetida

Aksheev Bhambri, Neeraj Dhaunta, Surendra Singh Patel, Mitali Hardikar, Nagesh Srikakulam, Shruti Shridhar, Shamsudheen Karuthedath Vellarikkal, Hemant Suryawanshi, Rajesh Pandey, Rijith Jayarajan, Ankit Verma, Vikram Kumar, Abhishek Bhatt, Pradeep Gautam, Manish Rai, , Beena Pillai

The paper presents genome, transcriptome, and metagenome data from Eisenia fetida to study regeneration dynamics, identifying differentially expressed genes and microbial communities.

bioRxiv · Aug 25, 2017 · PreprintGenomics