Whole genome duplication through mitotic slippage causes nuclear instability
Simon Gemble, Margot Budzyk, Anthony Y. Simon, Ruxandra A. Lambuta, Luca Nanni, Nicole Weiss, Audrey Forest, Yekaterina A. Miroshnikova, Federica Scotto di Carlo, Véronique Marthiens, C Verdel, Jing Fang, Chantal Desdouets, Sara A. Wickström, Giovanni Ciriello, , Renata Basto
The paper investigates how different routes to whole-genome duplication (WGD) affect nuclear stability, finding that mitotic slippage uniquely causes nuclear instability.
The EMBO Journal · Sep 19, 2026Peer-reviewedCell Biology