Pharmacology & ToxicologybioRxivPreprint
6-Methylnicotine is a strong agonist at α4β2 and α3β4 nicotinic cholinergic receptors
Thao T. Olson, Reniel Suarez Gonzalez, Yousef Aljohani…·Kenneth J. Kellar
This study compares 6-Methylnicotine and nicotine's effects on α4β2 and α3β4 nicotinic cholinergic receptors, finding 6-MN is more potent and upregulates these receptors.