Author

Mark P. Jedrychowski

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:multiome· 1

Frequent Co-Authors

Steven P. GygiiD· 2 shared Alec EamesiD· 1 shared Andreas ProkeschiD· 1 shared Anna Sofie HustediD· 1 shared Astrid Linde BasseiD· 1 shared Brice EmanuelliiD· 1 shared Cecilie Kynding KristenseniD· 1 shared David TandioiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMolecular Biology

Steven P. GygiORCID

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Author profile →

3 papers

Recent·Most cited

Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of interorganellar lipid cycling

Iuliia E. Karavaeva, Astrid Linde Basse, Samuel A.J. Trammell, Mohammed Faiz Hussain, Lasse Kruse Markussen, Jesper Foged Havelund, Marie Sophie Isidor, Hannah J. Richter, Sabina Chubanava, Yann Deleye, Zafir Kaiser, Yachen Shen, Ditte Neess, Frederike Sass, Fabian Finger, , Zachary Gerhart‐Hines

This paper identifies SLC25A34 as a key regulator of interorganellar lipid cycling, integrating circadian rhythms, diet, and temperature to control thermogenic metabolism.

bioRxiv · Jun 4, 2026 · PreprintMolecular Biology

Dynamic metabolic network modeling of a mammalian cell cycle using time-course multi-omics data

Ho‐Joon Lee, Fangzhou Shen, Alec Eames, Mark P. Jedrychowski, Sriram Chandrasekaran

The paper uses dynamic metabolic modeling to analyze time-course multi-omics data from murine pro-B cells, revealing key metabolic changes during the cell cycle.

bioRxiv · Oct 11, 2021 · PreprintSystems Biology

Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer's disease mouse model

Satoshi Muraoka, Mark P. Jedrychowski, Naotoshi Iwahara, Mohammad Abdullah, Kristen D. Onos, Kelly J. Keezer, Jianqiao Hu, Seiko Ikezu, Gareth R. Howell, Steven P. Gygi, Tsuneya Ikezu

The paper identifies enriched neurodegenerative microglia signatures in EVs from Alzheimer's disease mouse models using proteomic analysis.

Journal of Proteome Research · Feb 3, 2021Peer-reviewedNeuroscience