Author

Marshall Case

Primary ORCID profile (0000-0002-1504-4802 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Marshall CaseiD2 papers · University of Michigan

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Alena KhmelinskaiaiD· 1 shared Alex Reis· 1 shared Anna U. Macintyre· 1 shared Arash VahdatiD· 1 shared Bhoomika Basu MallikiD· 1 shared Christian DallagoiD· 1 shared Clara T. SchoederiD· 1 shared D. L. RIEGERiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Alena KhmelinskaiaORCID

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Author profile →

1 paper

Recent·Most cited

Latent generative search unlocks de novo design of untapped biomolecular interactions at scale

Kieran Didi, Danny Reidenbach, Matthew Penner, Supriya Ravichandran, Marshall Case, Mike Nichols, Erik Swanson, Alex Reis, Maggie Prescott, Yue Hong Qian, Dongming Qian, J.S. Yang, Weiji Li, Le Li, Daichi Shonai, , Karsten Kreis

Reward-guided inference-time search over the Proteína-Complexa sequence-structure codesign model yields validated binders across 127 targets, kinases and a free carbohydrate, with codesigned sequences outperforming ProteinMPNN redesign.

bioRxiv · Sep 18, 2026 · PreprintBioengineering✦ In-depth digest