PAIP1 couples mRNA export to cytoplasmic mRNP remodeling and poly(A) homeostasis
Daan Overwijn, Kerstin Dörner, Caroline De Almeida, Martin Mueller, Andrey A. Mironov, Robert Ivánek, Peter Škrinjar, Michelle Jennifer Gut, Isabel Solheim, Nicole Beuret, Thomas Bock, Matthias Zeug, Maciej Jerzy Smialek, Sina Brandkamp, Timm Maier, , Maria Hondele
This study identifies PAIP1 as a cofactor for mRNA export and shows it couples nuclear to cytoplasmic mRNP remodeling and poly(A) homeostasis, affecting mRNA stability and development.
bioRxiv · Aug 3, 2026 · PreprintMolecular Biology