Abnormal Lipid Metabolism and Altered Neuronal Support by Astrocytes Lacking Akap11, a Risk Gene for Schizophrenia and Bipolar Disorder
Xiao‐Man Liu, Horia Pribiag, Deeksha Misri, Kwanho Kim, Kira A. Perzel Mandell, Bryan J. Song, David R. Graykowski, Olivia Seidel, Nolan D. Hartley, Mateo Herrera, Haiyun Xu, Matthew Tegtmeyer, Yan-Ling Zhang, Lei Cui, Natalie M. Clark, , Morgan Sheng
This study identifies AKAP11's role in regulating lipid metabolism and neuronal support in astrocytes, linking its dysfunction to schizophrenia and bipolar disorder risk.
bioRxiv · Apr 25, 2025 · PreprintCell Biology