Process optimization for enhanced enzymatic nylon deconstruction
Célestin Bourgery, Lance X. Zhang, Dana L. Carper, Muchu Zhou, Robert L. Sacci, Matt Korey, Lei Wang, Jessica H.B. Hemond, John F. Cahill, Vera Bocharova, Joshua K. Michener
This study optimizes reaction conditions for three nylon-degrading enzymes, achieving high product titers for PA6 and PA66 without enzyme engineering or substrate pretreatment, and demonstrates scalability for complex PA-based materials.
bioRxiv · Nov 26, 2025 · PreprintBiochemistry