Author

Matthew Fisher

University of Sheffield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

David B. SykesiD· 2 shared Jennifer MunkleyiD· 2 shared Kirsty HodgsoniD· 2 shared Margarita Orozco‐MorenoiD· 2 shared Michelle Anne LawsoniD· 2 shared Ning WangiD· 2 shared Shenglin MeiiD· 2 shared Ziqian PengiD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

David B. SykesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Siglec-15 is a glyco-immune checkpoint in prostate cancer regulating immune evasion and metastasis

Nicoll Matthews, F. Zeng, Kirsty Hodgson, Matthew Fisher, Ziqian Peng, Libby Blencoe, Margarita Orozco‐Moreno, Ella P. Dennis, Liancheng Lu, Michelle Anne Lawson, Shenglin Mei, David B. Sykes, Dallas B. Flies, Richard Beatson, Ning Wang, Jennifer Munkley

Siglec-15 is found on prostate tumour cells, macrophages and osteoclasts; antibody blockade reduced macrophage immunosuppression, osteoclast formation and tumour growth in mice (CD8+ T-cell-dependent).

bioRxiv · Aug 10, 2026 · PreprintCancer Biology✦ In-depth digest

Siglec-engaging immunosuppressive sialoglycans are upregulated in prostate cancer and are targetable to suppress bone metastasis

Ziqian Peng, Kirsty Hodgson, Matthew Fisher, Shenglin Mei, Margarita Orozco‐Moreno, Lizhi Cao, Michael C. Kemp, Wayne Gatlin, Louisa Donald, Feier Zeng, Michelle Anne Lawson, Dániel Ungár, David B. Sykes, David J. Elliott, Li Peng, , Jennifer Munkley

This study identifies Siglec-engaging sialoglycans as upregulated in prostate cancer and shows they can be targeted to suppress bone metastasis using a bisialidase.

bioRxiv · Nov 12, 2025 · PreprintCancer Biology

Rac1 controls cell turnover and mammary gland reversibility in post-partum involution

Aleksander Mironov, Matthew Fisher, Randa Elsayed, Melis Karabulutoglu, Nasreen Akhtar

This study shows Rac1 regulates cell turnover and reversibility in mammary gland involution by controlling proliferation and cell death pathways.

bioRxiv · Feb 28, 2022 · PreprintDevelopmental Biology