Author

Matthew Goff

University of Utah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Esther NeediD· 2 shared Shreya GoeliD· 2 shared Sixiang ShiiD· 2 shared Amit M. MaityiD· 1 shared Anil K. SoodiD· 1 shared Ayden Berndt· 1 shared Carmine Schiavone· 1 shared David L. GillespieiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioengineering

Esther NeedORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

FOLR1-targeted Actinium-225-based Alpha-particle Therapy Eliminates Ovarian Cancer

Neetu Singh, Esther Need, Ayden Berndt, Matthew Goff, Lydia J. Wilson, Firas Mourtada, Feng Guo, Tara Mastren, Taslim Ahmed Al-Hilal, Anil K. Sood, Amit M. Maity, Scott C. Miller, Satoshi Minoshima, Shreya Goel, Sixiang Shi

This study demonstrates that FOLR1-targeted Actinium-225 alpha-particle therapy effectively treats ovarian cancer with high tumor regression and survival rates while minimizing toxicity.

Science Advances · Jun 24, 2026Peer-reviewedBioengineering

Image-Guided Targeting of Mitochondrial Metabolism Sensitizes Pediatric Malignant Rhabdoid Tumors to Low Dose Radiotherapy

Wenxi Xia, Matthew Goff, Carmine Schiavone, Neetu Singh, Jiemin Huang, Esther Need, Joseph Cave, David L. Gillespie, Randy L. Jensen, Marty D. Pagel, Prashant Dogra, Sixiang Shi, Shreya Goel

This study shows that targeting mitochondrial metabolism with Atovaquone enhances radiotherapy effectiveness in pediatric rhabdoid tumors by improving tumor oxygenation.

Science Advances · May 23, 2025Peer-reviewedBioengineering