Omics-scale capture of electrophilic metabolites
Allen F. Schroeder, Yan Yu, Ali Turk, Henry H. Le, Matthew LeClair, Marissa A. Fontaine, Nicholas W. Cheng, Saeideh Azad, Christopher N. Parkhurst, Jason Pan, David Artis, Meng Wang, Frank C. Schroeder
This paper introduces TAMOHA, a biochemical probe that enables comprehensive profiling of electrophilic metabolites, revealing thousands of previously uncharacterized species in E. coli, C. elegans, and mouse.
ACS Chemical Biology · Oct 2, 2026Peer-reviewedBiochemistry