In vivo nuclear envelope adaptation during cell migration across confining embryonic tissue environments
Hanna-Maria Häkkinen, Soraya Villaseca, Zain Alhashem, Szymon Chomiczewski, Maxime Desevedavy, Solene Leleux, Atrin Hamidzadeh, Filomena Gallo, Dina El-Zohiry, Victor Petre, Elena Scarpa
The paper investigates how neural crest cells adapt to physical confinement during migration in zebrafish embryos, finding that nuclear deformation occurs without DNA damage.
bioRxiv · Jun 5, 2025 · PreprintDevelopmental Biology