Author

Md Saiful Islam

Deutsches Konsortium für Translationale KrebsforschungPrimary ORCID profile (0000-0001-9842-0676 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Md Saiful IslamiD1 paper · MRC Laboratory of Molecular Biology

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

H. T. Marc TimmersiD· 1 shared Omid FotouhiiD· 1 shared Sheikh NizamuddiniD· 1 shared Stefanie Koidl· 1 shared Timothy En Haw ChaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

H. T. Marc TimmersORCID

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1 paper

Recent·Most cited

SMAD4 MH2 Mutations Disrupt CREBBP/EP300 Recruitment and TGF-β-Induced Transcription in Colorectal Cancer

Md Saiful Islam, Sheikh Nizamuddin, Timothy En Haw Chan, Omid Fotouhi, Stefanie Koidl, H. T. Marc Timmers

This study shows that SMAD4 MH2 mutations in colorectal cancer impair CREBBP/EP300 recruitment and TGF-β-induced transcription, explaining their loss-of-function effects.

bioRxiv · Jul 1, 2026 · PreprintCancer Biology