Rare genetic variants impact muscle strength
Yunfeng Huang, Dóra Bodnár, Chia‐Yen Chen, Gabriela Sánchez-Andrade, Mark Sanderson, Biogen Biobank Team, Christopher D. Whelan, Paola G. Bronson, David Sexton, Sally John, Eric Marshall, Mehool Patel, Saranya Duraisamy, Timothy Swan, Denis A. Baird, , Heiko Runz
This study identifies six genes associated with hand grip strength using rare protein-coding variants in 340,319 individuals and shows additive effects with common variants.
Nature Communications · Jun 10, 2023Peer-reviewedGenetic & Genomic Medicine