Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's disease
Hyo Lee, Richard V. Pearse, Alexandra M Lish, Cheryl Pan, Zachary M. Augur, Gizem Terzioğlu, Pallavi Gaur, Meichen Liao, Masashi Fujita, Earvin S. Tio, Duc Minh Duong, Daniel Felsky, Nicholas T. Seyfried, Vilas Menon, David A. Bennett, , Tracy L. Young‐Pearse
The paper uses iPSC-derived astrocytes to study genetic risk factors for Alzheimer's disease, finding concordant molecular changes in both astrocytes and brain tissue.
Glia · Feb 3, 2025Peer-reviewedNeuroscience