Author

Melanie Spanjaard

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Susanne Theiß· 2 shared Anna MalovannayaiD· 1 shared Antrix JainiD· 1 shared Azmal Syed Ali· 1 shared Baran E. GüleriD· 1 shared Celine E. de Esch· 1 shared Christian P. Schaaf· 1 shared Christian Patrick SchaafiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Susanne Theiß

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Multi-omics profiling reveals MAGEL2-driven defects in human corticogenesis shared across Prader-Willi and Schaaf-Yang syndromes.

Jannis Buecking, Baran E. Güler, Michael Eibl, Azmal Syed Ali, Tobias Walczuch, Tobias Beschauner, Susanne Theiß, Melanie Spanjaard, Katrin Hinderhofer, Freya Herrmann-Sim, Celine E. de Esch, Derek J.C. Tai, Michael E. Talkowski, Jeroen Krijgsveld, Christian P. Schaaf, Magdalena Laugsch

This study identifies MAGEL2-driven defects in human corticogenesis shared between Prader-Willi and Schaaf-Yang syndromes using multi-omics profiling of induced neurons.

bioRxiv · May 5, 2026 · PreprintNeuroscience

A truncating mutation of Magel2 in the rat modelled for the study of Schaaf-Yang and Prader-Willi syndromes alters select behavioral and physiological outcomes

Derek L. Reznik, Mingxiao V. Yang, Pedro Albelda de la Haza, Antrix Jain, Melanie Spanjaard, Susanne Theiß, Christian Patrick Schaaf, Anna Malovannaya, Theresa V. Strong, Surabi Veeraragavan, Rodney C. Samaco

This study generates and characterizes a rat model with a truncating Magel2 mutation, revealing altered behavioral and physiological traits consistent with human neurodevelopmental disorders.

bioRxiv · Aug 9, 2022 · PreprintNeuroscience