Aberrant gliogenesis and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
Dorit Trudler, Swagata Ghatak, Michael Bula, James Parker, Maria V. Talantova, Melissa Luevanos, Sergio R. Labra, Titas Grabauskas, Sarah Moore Noveral, Mayu Teranaka, Emily Schahrer, Nima Dolatabadi, Clare Bakker, Kevin M. Lopez, Abdullah Sultan, , Stuart A. Lipton
Autism-like MEF2C+/- patient hiPSC models show miRNA-mediated overproduction of astrocytes and hyperactivity of neurons.
Molecular Psychiatry · Sep 30, 2024Peer-reviewedNeuroscience