Ependymomas are cancers of the pre-neural crest/roof plate lineage
Polina Balin, Sachin A Kumar, Riley Galton, Alberto Delaidelli, Wilda Orisme, Parthiv Haldipur, Ncedile Mankahla, Amr M. Saadeldin, Nik von Krosigk, Maria Claudia Vladoiu, Anders Wilder Erickson, Meyer Barembaum, Jake Millman, Amy J Banks, Jeffrey T Joseph, , Michael D. Taylor
The paper identifies ependymomas as originating from the pre-neural crest/roof plate lineage using single-cell transcriptomics and lineage tracing.
bioRxiv · Jul 14, 2026 · PreprintDevelopmental Biology