Engineered living materials suppress uropathogenic E. coli growth and invasion of urothelial cells through sustained probiotic release
Manivannan Sivaperuman Kalairaj, Veerakit Vanitshavit, Iris George, Leroy Arthur, Mustafa K. Abdelrahman, Mason C Ansley, Samantha N Goebel, Konstantinos D Stamatis, Mia A Walling, Isabel K Murphy, Hayden E Wylie, Kenneth Hoyt, Philippe E. Zimmern, Sargurunathan Subashchandrabose, Taylor H. Ware
This paper develops an engineered living material that continuously releases probiotic E. coli to suppress uropathogenic E. coli growth and invasion of urothelial cells in vitro and in vivo.
bioRxiv · Sep 17, 2026 · PreprintBioengineering