Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells Within Distinct Zones
Ruochen Dong, Hua Li, Xi C. He, Wang Chen, Anoja G. Perera, Seth Malloy, Jonathon Russell, Wenting Li, Kaitlyn Petentler, Xinjian Mao, Zhe Yang, Michael Epp, Kate Hall, Allison R. Scott, Mary Cathleen McKinney, , Linheng Li
This study identifies two distinct multicellular niches in fetal liver and adult bone marrow that support hematopoietic stem cells with different cycling states and lineage biases.
bioRxiv · Jun 28, 2024 · PreprintDevelopmental Biology