Deletion of Lats 1 and 2 in mouse pancreatic acinar cells induces pancreatic fibrosis and inflammation
Ming Gao, Jun Liu, MICHAEL J. NIPPER, Francis E. Sharkey, Randy L. Johnson, Howard C. Crawford, Yidong Chen, Pei Wang
This study shows that deleting Lats1 and Lats2 in adult mouse pancreatic acinar cells causes fibrosis and inflammation through YAP1/TAZ activation.
bioRxiv · Jan 23, 2019 · PreprintMolecular Biology