Author

Michael Lachmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

fabrizio mafessoni· 1 shared Hang ZhouiD· 1 shared Jing Li· 1 shared Kun TangiD· 1 shared Li Jin· 1 shared Mark StonekingiD· 1 shared Philipp KhaitovichiD· 1 shared Qianhui Yu· 1 shared

Activity by Year

2015-2015 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperEvolutionary Biology

fabrizio mafessoni

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2 papers

Recent·Most cited

A Chronological Atlas of Natural Selection in the Human Genome during the Past Half-million Years

Hang Zhou, Sile Hu, Rostislav Matveev, Qianhui Yu, Jing Li, Philipp Khaitovich, Li Jin, Michael Lachmann, Mark Stoneking, Qiaomei Fu, Kun Tang

This study estimates the timing of natural selection in the human genome over the past half-million years, identifying selection events related to brain evolution and Alzheimer's disease pathways.

bioRxiv · Jun 19, 2015 · PreprintEvolutionary Biology

Selective strolls: fixation and extinction in diploids are slower for weakly selected mutations than for neutral ones

fabrizio mafessoni, Michael Lachmann

The paper shows that weakly selected mutations in diploids fix or go extinct more slowly than neutral ones due to dominance and recessivity, contradicting common assumptions about selection's effect.

bioRxiv · Mar 26, 2015Evolutionary Biology