Author

Michelle Arkin

Albert Einstein College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Adam L. BoxeriD· 1 shared Aishwarya C. Ballapuram· 1 shared Ana María CuervoiD· 1 shared Anna Karydas· 1 shared Benjamin F. CravattiD· 1 shared Benjamin J. HuangiD· 1 shared Boer Xie· 1 shared Bruce L. MilleriD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Adam L. BoxerORCID

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Author profile →

2 papers

Recent·Most cited

In vivo validation of the palmitoylation cycle as a therapeutic target in NRAS-mutant cancer

Matthew Decker, Benjamin J. Huang, Timothy B. Ware, Christopher D. Boone, Michelle Tang, Julia Ybarra, Matthew J. Sale, Rony A. Francois, Aishwarya C. Ballapuram, Katrine A. Taran, Esteban Tarazona-Guzman, Pan-Yu Chen, Marcos Armendariz, Camille J. Leung, Max Harris, , Kevin Shannon

This study validates the palmitoylation cycle as a therapeutic target in NRAS-mutant cancers by showing that inhibiting ABHD17 reduces tumor growth and synergizes with MEK inhibitors.

bioRxiv · Mar 20, 2025 · PreprintCancer Biology

Tau Secretion and Propagation Is Regulated by p300/CBP via Autophagy-Lysosomal Pathway in Tauopathy

Xu Chen, Yaqiao Li, Chao Wang, Yinyan Tang, Sue‐Ann Mok, Richard M. Tsai, Julio C. Rojas, Anna Karydas, Bruce L. Miller, Adam L. Boxer, Jason E. Gestwicki, Ana María Cuervo, Michelle Arkin, Li Gan

This study identifies p300/CBP as a regulator of tau secretion via the autophagy-lysosomal pathway, showing its role in tau propagation in tauopathies.

Molecular Neurodegeneration · Jan 6, 2020Peer-reviewedNeuroscience