Author

Mingxin Gu

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Synthetic Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Michael Cory BassikiD· 4 shared Alun Vaughan-JacksoniD· 2 shared Anshul Bharat KundajeiD· 2 shared Catherine R. ZhangiD· 2 shared Kaitlyn K. Spees· 2 shared Roarke A. KamberiD· 2 shared Adi Xiyal MukundiD· 1 shared Ahmad S. KhaliliD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersSynthetic Biology

Michael Cory BassikORCID

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Author profile →

4 papers

Recent·Most cited

Programmable synthetic cytokine receptors polarize macrophages to user-defined functional states

Judith C. Lunger, Lucas E. Sant’Anna, Antonio Salcido-Alcántar, Rebeca Arroyo Hornero, Wansang Cho, Alun Vaughan-Jackson, Mingxin Gu, Jenny Y Liu, Alexandra Beckett, Joaquin Parrilla-Garcia, Sneha Ramakrishna, Michael Cory Bassik, Kyle G. Daniels

This paper introduces a synthetic cytokine receptor platform that programmably polarizes macrophages to defined functional states, showing enhanced phagocytosis and tumor reduction in mice.

bioRxiv · May 14, 2026 · PreprintSynthetic Biology

Cancer cell phagocytosis induces an anti-inflammatory gene regulatory program in macrophages

Catherine R. Zhang, Lei Xiong, Mingxin Gu, Christine Y. Yeh, Livnat Jerby‐Arnon, Anshul Bharat Kundaje, William James Greenleaf, Michael Cory Bassik

This study shows that cancer cell phagocytosis by macrophages induces an anti-inflammatory gene regulatory program, promoting immunosuppression and tumor growth.

bioRxiv · Aug 18, 2025 · PreprintCancer Biology

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts

Josh Tycko, Mike V. Van, Aradhana, Nicole V. DelRosso, Hanrong Ye, David Yao, Raeline Valbuena, Alun Vaughan-Jackson, Xiaoshu Xu, Connor Ludwig, Kaitlyn K. Spees, Katherine Tin Heng Liu, Mingxin Gu, Venya Khare, Adi Xiyal Mukund, , Michael Cory Bassik

The paper develops HT-recruit to measure transcriptional effector function across contexts and identifies context-dependent effectors for CRISPR-based transcription control.

Nature Biotechnology · Nov 1, 2024Peer-reviewedSystems Biology

A genome-wide almanac of co-essential modules assigns function to uncharacterized genes

Michael Wainberg, Roarke A. Kamber, Akshay Balsubramani, Robin M. Meyers, Nasa Sinnott-Armstrong, Daniel Hornburg, Lihua Jiang, Joanne Chan, Ruiqi Jian, Mingxin Gu, Anna Shcherbina, Michael M. Dubreuil, Kaitlyn K. Spees, Wouter R. A. Meuleman, Michael P. Snyder, , Anshul Bharat Kundaje

This paper develops a statistical method to identify gene co-essentiality, creating a genome-wide functional module almanac that predicts functions for 102 uncharacterized genes and validates key findings.

Nature Genetics · Apr 15, 2021Peer-reviewedGenomics