Author

Mohammad Saki

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Frank PajonkiD· 5 shared Ling HeiD· 5 shared Kruttika BhatiD· 4 shared Angeliki Diotima IoannidisiD· 3 shared Harley I. KornblumiD· 3 shared Linda M. LiauiD· 3 shared Fei ChengiD· 2 shared Le ZhangiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersNeuroscience

Frank PajonkORCID

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Author profile →

5 papers

Recent·Most cited

Repurposing Quetiapine as an Adjuvant Therapeutic Agent for Triple-Negative Breast Cancer

Ling He, Purva Joshi, Angeliki Diotima Ioannidis, Anoushka Kathiravan, Mohammad Saki, Frank Pajonk

This study evaluates quetiapine as an adjuvant therapy for triple-negative breast cancer, showing it reduces clonogenicity, promotes apoptosis, and impairs DNA repair and migration.

Radiation Research · Apr 23, 2026Peer-reviewedCancer Biology

Combined quetiapine and radiation therapy approach to treat mesothelioma-initiating cells and increase survival in a mouse model of mesothelioma

Anjelica M. Cardenas, Evelyn Arambula, Linda Azizi, Tara Lam, Sabrina Sutlief, Kruttika Bhat, Mohammad Saki, Ling He, Frank Pajonk

This study shows that combining quetiapine and radiation therapy reduces mesothelioma-initiating cells and improves survival in a mouse model of mesothelioma.

bioRxiv · Apr 8, 2025 · PreprintCancer Biology

Combined Treatment with Dopamine Receptor Antagonists and Radiation Creates a Metabolic Vulnerability in Mouse Models of Glioblastoma

Kruttika Bhat, Mohammad Saki, Fei Cheng, Ling He, Le Zhang, Angeliki Diotima Ioannidis, David A. Nathanson, Jonathan Tsang, Steven J. Bensinger, Phioanh Leia Nghiemphu, Timothy Francis Cloughesy, Linda M. Liau, Harley I. Kornblum, Frank Pajonk

This study shows that combining quetiapine, atorvastatin, and radiation extends survival in glioblastoma mouse models by exploiting a metabolic vulnerability.

JNCI Journal of the National Cancer Institute · Feb 3, 2021Peer-reviewedNeuroscience

The Dopamine Receptor Antagonist TFP Prevents Phenotype Conversion and Improves Survival in Mouse Models of Glioblastoma

Kruttika Bhat, Mohammad Saki, Erina Vlashi, Fei Cheng, Sara Duhachek-Muggy, Claudia Alli, Guoxing Yu, Paul Medina, Ling He, Robert D. Damoiseaux, Matteo A. Pellegrini, Nathan R. Zemke, Phioanh Leia Nghiemphu, Timothy Francis Cloughesy, Linda M. Liau, , Frank Pajonk

Proceedings of the National Academy of Sciences · May 1, 2020Peer-reviewedNeuroscience

1--4-phenylpiperazine Treatment After Brain Irradiation Preserves Cognitive Function in Mice

Kruttika Bhat, Paul Medina, Ling He, Le Zhang, Mohammad Saki, Angeliki Diotima Ioannidis, Nhan T. Nguyen, Sirajbir S. Sodhi, David Sung, Clara E. Magyar, Linda M. Liau, Harley I. Kornblum, Frank Pajonk

This paper shows that Compound #5 reduces radiation-induced cognitive decline in mice without affecting tumor growth.

Neuro-Oncology · Apr 13, 2020Peer-reviewedNeuroscience