Fluoxetine-induced neurogenesis and chronic antidepressant effects requires the dopamine D2 receptor.
Gohar Fakhfouri, Morgane Lemasson, Stella Manta, Quentin Rainer, Mohammad Reza Zirak, Bruno Giros A, Jean‐Martin Beaulieu
This study shows that chronic fluoxetine's antidepressant effects and neurogenesis require the dopamine D2 receptor, with implications for treatment response and drug interactions.
bioRxiv · Mar 31, 2026 · PreprintNeuroscience