Structural basis of eIF4E recognition of synthetic mRNA 5' cap analogues links cap architecture to affinity and biological activity
Sabine Schneider, Sarah Moreno, Moritz Thran, Rainer Joachim Schwarz
This study investigates how synthetic 5' cap analogues interact with eIF4E, revealing structural features that influence mRNA translation efficiency and biological activity.
bioRxiv · Oct 6, 2026 · PreprintBiochemistry