Evolutionary analysis of Quinone Reductases 1 and 2 suggest that NQO2 evolved to function as a pseudoenzyme
F. Islam, N. Basilone, E. H. Ball, B. H. Shilton
This study shows NQO2 evolved to have low catalytic efficiency with NADH, while NQO1 evolved high efficiency, suggesting functional divergence between the two enzymes.
bioRxiv · Nov 11, 2022Biochemistry