Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP·Kap114·H2A-H2B complex
J. Jiou, J. M. Shaffer, N. Bernardes, H. Y. J. Fung, J. Kikumoto Dias, S. D'Arcy, Y. M. Chook
This paper reveals the structure of the RanGTP·Kap114·H2A-H2B complex and explains how RanGTP primes H2A-H2B release for nucleosome assembly.
bioRxiv · Nov 22, 2022Biochemistry