Phosphoproteomic mapping reveals distinct signaling actions and activation of protein synthesis and muscle hypertrophy by Isthmin-1
M. Zhao, N. B. Dannieskiold-Samsoee, L. Ulicna, Q. Nguyen, L. Voilquin, D. E. Lee, J. P. White, Z. Jiang, N. Cuthbert, S. Paramasivam, E. Bielczyk-Maczynska, C. Van Rechem, K. J. Svensson
This study identifies distinct phosphoproteomic effects of Ism1 compared to insulin, revealing novel pathways in muscle hypertrophy and protein synthesis.
bioRxiv · May 19, 2022Cell Biology