Cell contractility-induced mechanical stress triggers eIF2α-regulated translation during early adhesion of mesenchymal-like cells
A. Caillier, M. Lavigne, J. Bergeman, N. Morin, F. Rondeau, J. Gouhier, B. Trudel, J.-P. Lambert, R. Mazroui, F. Bordeleau, M.-E. Huot
The paper identifies a mechanotransduction pathway where eIF2α phosphorylation during early adhesion regulates selective translation of proteins critical for adhesion and contractility in mesenchymal-like cells.
bioRxiv · Apr 19, 2022 · PreprintCell Biology