OTUB1 non-catalytically regulates the stability of the E2 ubiquitin conjugating enzyme UBE2E1
N. Pasupala, M. E. Morrow, L. T. Que, B. A. Malynn, A. Ma, C. Wolberger
This study identifies a non-catalytic role of OTUB1 in stabilizing the E2 ubiquitin conjugating enzyme UBE2E1 by preventing its autoubiquitination and proteasomal degradation.
bioRxiv · Jun 29, 2018Cell Biology