OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection
E. Hortle, L. V. Tran, A. R. Fontaine, N. Pinello, J. J. Wong, W. J. Britton, S. H. Oehlers
This study shows that OXSR1 limits potassium efflux during mycobacterial infection, thereby inhibiting inflammasome activation and reducing bacterial burden.
bioRxiv · Apr 21, 2021Immunology