Radiolabeling of PSMA-617 with 89Zr: A Novel Use of DMSO for Radiochemical Yield Enhancement and Preliminary Small-Animal PET Results
R. Imura, A. N. Ozeki, N. Shida, M. Kobayashi, H. Ida, Y. Wada, N. Akimitsu, Y. Kumakura
This paper reports the radiolabeling of PSMA-617 with 89Zr using DMSO and HEPES buffer, achieving a 70% radiochemical yield and demonstrating PET imaging of LNCaP tumors without bladder accumulation.
bioRxiv · Jun 28, 2021Cancer Biology