M. Kobayashi

Development of a 3D vascular network visualization platform for one-dimensional hemodynamic simulation

This paper develops a 3D vascular network visualization platform for 1D-0D hemodynamic simulations, demonstrating its use in surgical planning and complication prevention.

Discovery of the apiosyltransferase, celery UGT94AX1 that catalyzes the biosynthesis of a flavone glycoside, apiin

This paper identifies celery UGT94AX1 as the apiosyltransferase responsible for apiin biosynthesis and characterizes its substrate specificity and key residues.

Spring growth variation in pioneer and fibrous roots in Abies sachalinensis seedlings from provenances with contrasting snow cover environments

This study examines intraspecific variation in root growth dynamics of Abies sachalinensis seedlings from contrasting snow cover provenances, finding differences in morphological and structural traits of pioneer and fibrous roots.

Disentangling the complex gene interaction networks between rice and the blast fungus identifies a new pathogen effector

AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewings sarcoma cells

The paper identifies AHDC1 as a protein interacting with EWS-FLI1 in Ewing's sarcoma and shows its knockdown reduces cell growth and transcriptional activity.

A Jacalin-like lectin-domain-containing protein of Sclerospora graminicola act as an apoplastic virulence effector in plant-oomycete interactions

This study identifies SgJRL proteins from Sclerospora graminicola as apoplastic virulence effectors that suppress plant defense responses during infection.

DOMINANT AWN INHIBITOR encodes the ALOG protein originating from gene duplication and inhibits awn elongation by suppressing cell proliferation and elongation in sorghum

This study identifies DAI, a dominant awn inhibitor in sorghum, which originated from gene duplication and suppresses awn elongation by inhibiting cell proliferation and elongation.

Milk casein prevents inactivation effect of black tea galloylated theaflavins on SARS-CoV-2 in vitro

This study shows that milk casein prevents black tea's ability to inactivate SARS-CoV-2 variants in vitro, suggesting milk may reduce the antiviral effect of black tea.

A genetically linked pair of NLR immune receptors show contrasting patterns of evolution

This paper studies the evolution of a rice NLR gene pair, showing that the sensor NLR undergoes dynamic domain integration under balancing selection, while the helper NLR remains functionally conserved under purifying selection.

Radiolabeling of PSMA-617 with 89Zr: A Novel Use of DMSO for Radiochemical Yield Enhancement and Preliminary Small-Animal PET Results

This paper reports the radiolabeling of PSMA-617 with 89Zr using DMSO and HEPES buffer, achieving a 70% radiochemical yield and demonstrating PET imaging of LNCaP tumors without bladder accumulation.

SMURF2 phosphorylation at Thr249 modifies the stemness and tumorigenicity of glioma stem cells by regulating TGF-β receptor stability

This study shows that SMURF2 phosphorylation at Thr249 regulates GSC stemness and tumorigenicity by affecting TGF-β receptor stability.

Effect of luminal surface structure of decellularized aorta on thrombus formation and cell behavior

The paper investigates how the luminal surface structure of decellularized aorta affects thrombus formation and cell behavior, finding that structures closer to native aorta show better anti-coagulant properties and cell recognition.

Rapid inactivation in vitro of SARS-CoV-2 in saliva by black tea and green tea

This study shows that black and green tea can inactivate SARS-CoV-2 in saliva within 10 seconds, suggesting potential for reducing viral spread.

Significant inactivation of SARS-CoV-2 by a green tea catechin, a catechin-derivative and galloylated theaflavins in vitro

The paper investigates the in vitro antiviral effects of green tea and its derivatives against SARS-CoV-2, finding that certain compounds significantly reduce virus infectivity.

Properties of rhizosphere soil associated with herbaceous plant roots analyzed using small-scale protocols

The study compares nutrient mineral content between bulk and rhizosphere soils of sorghum, finding higher nutrient concentrations in rhizosphere soil.

Efficacy and safety of a monodisperse solid-in-oil-in-water emulsion in transcatheter arterial chemoembolization in a rabbit VX2 tumor model

This study evaluates a monodisperse miriplatin-Lipiodol emulsion in a rabbit VX2 tumor model, showing improved Lipiodol retention and no significant adverse events compared to a conventional suspension.

Mutant p53 Drives Clonal Hematopoiesis through Modulating Epigenetic Pathway

This study identifies mutant p53's role in promoting clonal hematopoiesis by modulating the EZH2-mediated epigenetic pathway.

Repeated inversions at the pannier intron drive diversification of intraspecific colour patterns of ladybird beetles

The paper identifies pannier as a key regulatory gene for color pattern variation in ladybird beetles and shows that inversions and cis-regulatory changes at this gene drive intraspecific diversity.