Author

N. Tsyba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 2

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Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:development & morphogenesis· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

M. R. Patel· 2 shared A. Z. Schwartz· 1 shared J. Nance· 1 shared Y. Abdu· 1 shared

Activity by Year

2021-2022 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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2 shared papersCell Biology

M. R. Patel

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2 papers

Recent·Most cited

Independent regulation of mtDNA quantity and quality resets the mitochondrial genome in C. elegans primordial germ cells

A. Z. Schwartz, N. Tsyba, Y. Abdu, M. R. Patel, J. Nance

The paper shows that C. elegans primordial germ cells use separate mechanisms to control mtDNA quantity and quality, resetting the mitochondrial genome.

bioRxiv · May 6, 2022Cell Biology

Tissue-specific heteroplasmy dynamics is accompanied by a sharp drop in mtDNA copy number during development

N. Tsyba, M. R. Patel

The paper measures heteroplasmy levels and mtDNA copy number in C. elegans neurons and muscles during development, finding tissue-specific differences and significant mtDNA loss.

bioRxiv · Jul 30, 2021 · PreprintCell Biology