Evolution of Origin Sequence and Recognition for Licensing of Eukaryotic DNA Replication
Jack Bauer, Narges Zali, Om Prakash Chouhan, Osama E. Demerdash, Kaiser Loell, Mathew Tuttle, Justin B. Kinney, Leemor Joshua‐Tor, Bruce Stillman
The paper compares origin recognition mechanisms in yeast and human cells, revealing evolutionary differences in DNA replication initiation.
bioRxiv · Aug 5, 2026 · PreprintMolecular Biology